You'll need to get your hands on some prickly pear syrup (easily purchased online) first, but you'll be glad you did. It creates a gorgeous fuchsia-colored margarita, and the flavor is sweet - almost like a more concentrated watermelon or berry vibe.
1/4 cup fresh orange juice (about 1 large orange)
3/4 cup fresh lime juice (about 5 limes)
1 cup tequila
1/2 cup orange liqueur (Patron Orange or Cointreau)
1/2 cup prickly pear syrup
Combine all ingredients in a pitcher. Serve and enjoy!
Recipe by 20something cupcakes at http://www.20somethingcupcakes.com/2012/06/prickly-pear-margaritas/